Вплив імпульсного низькоінтенсивного ультразвуку на остеоінтеграцію імплантатів (огляд літератури)

Abstract

The analysis and systematization of scientific researches results (experimental and clinical) considering the osteointegration peculiarities of orthopaedic implants under the conditions of low intensity impulse ultrasound exposure is represented in the review. A brief characteristic of the ultrasound, of its penetrability into the human tissues and of the factors influencing its penetrability is given. The values of ultrasound intensities used in the medicine with different aims are represented. A number of effects which are characteristic of ultrasound and which appear during its absorption and dissemination within some particular ambience are briefly represented. The definition for the term osteointegration is given and also for those processes which take place on the bone-implant border at the cellar and molecular levels. The meaning of vascularization and cellar osteogenic differentiation in the titanium samples implantation area under the conditions of different intensity impulse ultrasound application is explained. The experimental and scientific researches about the impulse ultrasound effect on the cultivated osteogenic cells and also on the osteoreparation optimization in the implantation area of different samples, which consist of different biomaterials as bone transplantats, bioceramics materials, and also metal samples are discussed. The generalized data showed that the low intensity impulse ultrasound (30-50 mV/cm2 and at frequency 1.0 or 1.5 MHz) does not negatively influence on the surface structure and biodegradation of the researched biomaterials and positively influences on the intimate contact formation, i.e. on the implants osteointegration and transplantats reconstruction that was shown as the earlier formation and ripening of the bone tissue in the implantation area and as the presence of accurate bigger bone tissue areas on the implants surface and in its pores.Unsolved issues connected with the ultrasound usage as the osteointegration optimizing factor in the field of biomaterials implantation.

The analysis and systematization of scientific researches results (experimental and clinical) considering the osteointegration peculiarities of orthopaedic implants under the conditions of low intensity impulse ultrasound exposure is represented in the review. A brief characteristic of the ultrasound, of its penetrability into the human tissues and of the factors influencing its penetrability is given. The values of ultrasound intensities used in the medicine with different aims are represented. A number of effects which are characteristic of ultrasound and which appear during its absorption and dissemination within some particular ambience are briefly represented. The definition for the term osteointegration is given and also for those processes which take place on the bone-implant border at the cellar and molecular levels. The meaning of vascularization and cellar osteogenic differentiation in the titanium samples implantation area under the conditions of different intensity impulse ultrasound application is explained. The experimental and scientific researches about the impulse ultrasound effect on the cultivated osteogenic cells and also on the osteoreparation optimization in the implantation area of different samples, which consist of different biomaterials as bone transplantats, bioceramics materials, and also metal samples are discussed. The generalized data showed that the low intensity impulse ultrasound (30-50 mV/cm2 and at frequency 1.0 or 1.5 MHz) does not negatively influence on the surface structure and biodegradation of the researched biomaterials and positively influences on the intimate contact formation, i.e. on the implants osteointegration and transplantats reconstruction that was shown as the earlier formation and ripening of the bone tissue in the implantation area and as the presence of accurate bigger bone tissue areas on the implants surface and in its pores.Unsolved issues connected with the ultrasound usage as the osteointegration optimizing factor in the field of biomaterials implantation.

The analysis and systematization of scientific researches results (experimental and clinical) considering the osteointegration peculiarities of orthopaedic implants under the conditions of low intensity impulse ultrasound exposure is represented in the review. A brief characteristic of the ultrasound, of its penetrability into the human tissues and of the factors influencing its penetrability is given. The values of ultrasound intensities used in the medicine with different aims are represented. A number of effects which are characteristic of ultrasound and which appear during its absorption and dissemination within some particular ambience are briefly represented. The definition for the term osteointegration is given and also for those processes which take place on the bone-implant border at the cellar and molecular levels. The meaning of vascularization and cellar osteogenic differentiation in the titanium samples implantation area under the conditions of different intensity impulse ultrasound application is explained. The experimental and scientific researches about the impulse ultrasound effect on the cultivated osteogenic cells and also on the osteoreparation optimization in the implantation area of different samples, which consist of different biomaterials as bone transplantats, bioceramics materials, and also metal samples are discussed. The generalized data showed that the low intensity impulse ultrasound (30-50 mV/cm2 and at frequency 1.0 or 1.5 MHz) does not negatively influence on the surface structure and biodegradation of the researched biomaterials and positively influences on the intimate contact formation, i.e. on the implants osteointegration and transplantats reconstruction that was shown as the earlier formation and ripening of the bone tissue in the implantation area and as the presence of accurate bigger bone tissue areas on the implants surface and in its pores.Unsolved issues connected with the ultrasound usage as the osteointegration optimizing factor in the field of biomaterials implantation.